Alanyl-glutamine dipeptide inhibits hepatic ischemia-reperfusion injury in rats
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منابع مشابه
Preconditioning with L-alanyl-glutamine reduces hepatic ischemia-reperfusion injury in rats.
PURPOSE To evaluate the effects of pre-conditioning with L-alanyl-glutamine (L-Ala-Gln) in rats subjected to total hepatic ischemia. METHODS Thirty Wistar rats, average weight 300g, were randomly assigned to 3 groups (n=10): G-1--saline, G-2--L-Ala-Gln, G-3--control (Sham). G-1 and G-3 groups were treated with saline 2.0 ml or L-Ala-Gln (0.75mg/Kg) intraperitoneally (ip) respectively, 2 hours...
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BACKGROUND Previous studies showed that cyclooxygenase(COX) was involved in ischemia/reperfusion (I/R) injuries. Parecoxib, a selective inhibitor for COX -2, has been shown to have protective properties in reducing I/R injury in the heart, kidney and brain. The aim of this study was to investigate the effects of parecoxib on hepatic I/R and to explore the underlying mechanisms. METHODS Fifty-...
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ژورنال
عنوان ژورنال: World Journal of Gastroenterology
سال: 2006
ISSN: 1007-9327
DOI: 10.3748/wjg.v12.i9.1373